Behavioral effects of thebaine in the rhesus monkey
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منابع مشابه
Behavioral effects of thebaine in the rhesus monkey.
Three experiments were conducted with rhesus monkeys to assess some behavioral effects of the opium alkaloid, thebaine, in relation to its dependence liability. The concurrent intramuscular administration of naloxone did not antagonize the rate-decreasing effects of thebaine on a fixed-ratio (FR) schedule of food-reinforced responding. Animals trained to self-administer codeine (0.3 mg/kg/inj) ...
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In rhesus monkeys, acute administration of levonantradol and nantradol produced signs of CNS depression, including ataxia with body sag, pupil dilation, ptosis, dozing, and reduced responsivity to external stimuli. Neither compound suppressed the morphine withdrawal syndrome; however, both alleviated the chronic abdominal contraction associated with withdrawal. The directly observable effects o...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 1981
ISSN: 0091-3057
DOI: 10.1016/0091-3057(81)90364-6